The secret of eternal youth is no doubt at the top of Madonna's wish list for her 50th birthday celebrations on Saturday.
Yet in the absence of such a discovery, Guy Ritchie is planning the next best thing.
The Mail has learned that Ritchie has decided to bow to pressure from his domineering wife and finally agree to try to bring another baby into their lives.
Ritchie will pledge his full support for her dream to adopt another child - this time a little girl - when the family celebrate Madonna's half-century with a small gathering next weekend.
The couple will now plough ahead with the adoption of a three-year-old girl from Malawi they were looking into when their marriage allegedly hit the rocks.
Adoption officials in Malawi have confirmed that Madonna was resuming her bid to adopt little Mercy James.